CasNo： 328898-40-4
MF： C41H71N3O8
The invention discloses a synthesis and ...
The invention discloses 20,23-dihalogena...
The invention discloses a synthetic meth...
The invention relates to a preparation m...
piperidine
20,23-diiodo-5-O-mycaminosyl tylonolide
20,23-dipiperidin-5-O-mycaminosyl tylonolide
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
dichloromethane;
at -5 - 45 ℃;
for 5h;
|
72.5% |
|
With
potassium carbonate;
In
dichloromethane;
at -5 - 45 ℃;
for 5h;
|
72.5% |
piperidine
C31H49NO10
20,23-dipiperidin-5-O-mycaminosyl tylonolide
| Conditions | Yield |
|---|---|
|
With
formic acid;
In
cyclohexane;
Concentration;
Reflux;
|
87.2% |
piperidine
(4R,5S,6S,7R,9R,11E,13E,15S,16R)-6-(((2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-15-(iodomethyl)-5,9,13-trimethyl-7-(2-(piperidin-1-yl)ethyl)oxacyclohexadeca-11,13-diene-2,10-dione
(11E,13E)-(4R,5S,6S,7R,9R,15R,16R)-6-((2R,3R,4S,5S,6R)-4-Dimethylamino-3,5-dihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-16-ethyl-4-hydroxy-7-(2-hydroxy-ethyl)-15-hydroxymethyl-5,9,13-trimethyl-oxacyclohexadeca-11,13-diene-2,10-dione
20-piperidinyl-tylosin
