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CasNo: 220119-17-5
MF: C43H63NO11
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Selamectin is , while it's Molecular Formula is C43H63NO11. Selamectin is a semi-synthetic avermectin derivative prepared by selective hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of endo- and exo- parasites of domestic animals, notably cats and dogs. Like the other milbemycin/avermectins, selamectin selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.
The CAS number of Selamectin is 220119-17-5.
More information of Selamectin 220119-17-5 are:
Synonyms |
Selamectin;Revolution;Stronghold;UNII-A2669OWX9N;LS-187010;UK-124,114; |
CAS Number |
220119-17-5 |
Molecular Formula |
C43H63NO11 |
Molecular Weight |
769.973 |
Density |
1.35 g/cm3 |
Boiling Point |
917 °C at 760 mmHg |
Flash Point |
508.4 °C |
HS CODE |
2932206000 |
PSA |
154.73000 |
LogP |
6.06980 |
Pka |
10.34±0.70(Predicted) |
Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. At 0.1 μg/ml, selamectin is reported to inhibit growth in an H. contortus larval development assay.
InChI:InChI=1/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30,40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11,14-15,19,24,26,28-29,31-35,37-40,45,47-48H,7-9,12-13,16-18,20-23H2,1-6H3/b11-10+,25-15+,30-14+,44-36-/t24-,26-,28-,31+,32-,33-,34-,35?,37?,38-,39-,40+,42+,43+/m0/s1
Articles related to Selamectin:
Article |
Source |
New Selamectin Intermediates, Preparation Method Thereof And Preparation Method For Selamectin Using The Same |
- Paragraph 0058; 0097-0100, (2019/07/05) |
Preparation method of selamectin |
- Paragraph 0053; 0054; 0055; 0072; 0073; 0074, (2017/09/18) |
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