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CasNo: 56-12-2
MF: C4H9NO2
Appearance: White microcrystalline powder
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4-Aminobutyric acid (GABA) is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. Although chemically it is an amino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term "amino acid," used without a qualifier, conventionally refers to the alpha amino acids, which GABA is not, nor is it ever incorporated into a protein. In spastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition's upper motor neuron lesion, which leads to hypertonia of the muscles signaled by those nerves that can no longer absorb GABA.
4-Aminobutyric acid is an important inhibitory neurotransmitter in the central nervous system, which has good water solubility and thermal stability. It has been confirmed that GABA, as a small molecular weight non protein amino acid, has edible safety and can be used in the production of beverages and other foods. Studies have shown that a certain amount of GABA can improve the body's sleep quality and reduce blood pressure.The foods contain γ-aminobutyric acid (GABA) at an amount that shows immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity.
The CAS number of 4-Aminobutyric acid is 56-12-2.
More information of 4-Aminobutyric acid 56-12-2 are:
CAS Number |
56-12-2 |
Density |
1.11 g/cm3 |
Melting Point |
195 °C (dec.)(lit.) |
Boiling Point |
247.985 °C at 760 mmHg |
Flash Point |
103.778 °C |
Vapor Pressure |
0.00798mmHg at 25°C |
Refractive Index |
1.4650 (estimate) |
HS CODE |
29224995 |
PSA |
63.32000 |
LogP |
0.51020 |
Pka |
4.031(at 25℃) |
The chemical formula of 4-Aminobutyric acid is C4H9NO2 which containing 4 Carbon atoms,9 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of 4-Aminobutyric acid is 103.121
4-Aminobutyric acid (GABA) is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. Although chemically it is an amino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term "amino acid," used without a qualifier, conventionally refers to the alpha amino acids, which GABA is not, nor is it ever incorporated into a protein. In spastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition's upper motor neuron lesion, which leads to hypertonia of the muscles signaled by those nerves that can no longer absorb GABA.
InChI:InChI=1/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
Relevant articles related to 4-Aminobutyric acid:
Article |
Source |
Enhancing effect of macroporous adsorption resin on gamma-aminobutyric acid production by Enterococcus faecium in whole-cell biotransformation system |
Yang, Sheng-Yuan,Liu, Shu-Min,Jiang, Min,Wang, Biao-Shi,Peng, Luo-Hui,Zeng, Chan , p. 771 - 780 (2020) |
Mechanistic aspects of uncatalyzed and ruthenium(III) catalyzed oxidation of DL-ornithine monohydrochloride by silver(III) periodate complex in aqueous alkaline medium |
Malode, Shweta J.,Abbar, Jyothi C.,Nandibewoor, Sharanappa T. , p. 2430 - 2442 (2010) |
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