• Product NameGrapiprant
  • CasNo. 415903-37-6
  • MFC26H29N5O3S
  • MW491.61
  • Purity
  • Appearance
  • Packing
  • Contact usInquiry

Product Details

CasNo: 415903-37-6

MF: C26H29N5O3S

Cost-effective customized wholesale Grapiprant 415903-37-6

  • Molecular Formula:C26H29N5O3S
  • Molecular Weight:491.61
  • PKA:5.19±0.10(Predicted) 
  • PSA:114.36000 
  • Density:1.29±0.1 g/cm3(Predicted) 
  • LogP:6.00130 

415903-37-6 Relevant articles

PROCESS FOR PREPARATION OF GRAPIPRANT

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Paragraph 0136, (2021/03/19)

The invention relates to process for the...

EP4 INHIBITORS AND SYNTHESIS THEREOF

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, (2020/02/06)

The present invention provides N-((4-(2-...

GRAPIPRANT UNIT DOSAGE FORMS

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Paragraph 00580; 00584, (2020/05/12)

The present invention provides grapipran...

EP4 INHIBITORS AND USE THEREOF

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Paragraph 0875-0882, (2019/10/29)

The present invention provides use of an...

415903-37-6 Process route

Tosyl isocyanate
4083-64-1

Tosyl isocyanate

CJ-023423
415903-37-6

CJ-023423

Conditions
Conditions Yield
2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethylamine hydrochloride; With sodium hydroxide; In dichloromethane; water; at 30 ℃; for 1.5h;
Tosyl isocyanate; In dichloromethane; at 10 - 25 ℃; for 1h; Product distribution / selectivity;
83.4%
Tosylurethane
5577-13-9

Tosylurethane

2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethylamine
415908-96-2

2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethylamine

CJ-023423
415903-37-6

CJ-023423

Conditions
Conditions Yield
With triethylamine; In toluene; at 80 - 90 ℃; for 4h;

415903-37-6 Upstream products

  • 415908-96-2
    415908-96-2

    2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethylamine

  • 4083-64-1
    4083-64-1

    Tosyl isocyanate

  • 415908-93-9
    415908-93-9

    2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethanol

  • 13472-00-9
    13472-00-9

    p-Aminophenethylamine

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