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  • Product NameGadoxetate Disodium
  • CasNo. 135326-22-6
  • MFC23H28GdN3Na2O11
  • MW725.718
  • Purity
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Product Details

CasNo： 135326-22-6

MF： C23H28GdN3Na2O11

Manufacturers supply cost-effective and customizable Gadoxetate Disodium 135326-22-6

  • Molecular Formula:C23H28GdN3O11*2Na
  • Molecular Weight:725.718
  • PSA：191.91000 
  • LogP:-3.91280 

135326-22-6 Relevant articles

Synthesis and physicochemical characterization of a new gadolinium chelate: The liver-specific magnetic resonance imaging contrast agent Gd-EOB-DTPA

Schmitt-Willich,Brehm,Ewers,Michl,Mueller-Fahrnow,Petrov,Platzek,Raduechel,Suelzle

, p. 1134 - 1144 (2008/10/08)

A convenient synthesis of disodium ,S-[4...

135326-22-6 Process route

gadolinium(III) oxide

gadolinium(III) oxide

sodium hydroxide
1310-73-2

sodium hydroxide

disodium S-[4-(4-ethoxybenzyl)-3,6,9-tris[(carboxy-κO)methyl]-3,6,9-triazaundecandioato(5-)-κ(3)N(3),N(6),N(9),κ(2)O(1),O(11)]gadolinate(2-)
135326-22-6

disodium S-[4-(4-ethoxybenzyl)-3,6,9-tris[(carboxy-κO)methyl]-3,6,9-triazaundecandioato(5-)-κ(3)N(3),N(6),N(9),κ(2)O(1),O(11)]gadolinate(2-)

Conditions
Conditions Yield
With C4H7(CH2C6H4OEt)N3(CH2CO2H)3, mixed sodium salt; In water; stoich. amts. of Gd2O3 and ligand, stirring at 80°C for 1 h, filtration, pH-adjustment to 7.0 with 1 M NaOH; concn. (vac.), EtOH addn., addn. to excess EtOH, refluxing for 2 h, collection (filtration), washing (95% EtOH), drying (vac., 50°C); elem. anal.; separable into two pairs of diastereomers by HPLC (Hypersil ODS, MeCN/aq. Bu4NOH);
82.2%

135326-22-6 Upstream products

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